Structural formula
| Business number | 03WY |
|---|---|
| Molecular formula | C22H28F3N3OSCl2 |
| Molecular weight | 510.44 |
| label |
Fluphenazine hydrochloride, flufuxamine impurities, Fluphenazine hydrochloride, Flufenazine hydrochloride, 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride |
Numbering system
CAS number:146-56-5
MDL number:MFCD00055212
EINECS number:205-674-1
RTECS number:TL9800000
BRN number:None
PubChem number:24277916
Physical property data
1. Physical property data:
1. Appearance: White or off-white crystalline powder. Fluphenazine ([69-23-8]) is a dark brown oily liquid.
2. Boiling point268-274℃ (66.5 ).
3. Melting point 226-233℃ (decomposition).
4. Easily soluble in water, slightly soluble in ethanol, very slightly soluble in acetone, insoluble in benzene and ether.
Toxicological data
2. Toxicological data:
1, acute toxicity: mice oral LD50: 220 mg/kg;
Mouse abdominal cavity LD50: 89 mg/kg;
Mouse intravenous LD50: 56 mg/kg.
2. Reproductive toxicity: Mouse oral TDLo: 10 mg/kg
Ecological data
3. Ecological data:
Other harmful Effect: This substance may be harmful to the environment, and special attention should be paid to water bodies.
Molecular structure data
5. Molecular property data:
1. Molar refractive index:114.30
2. Molar volume (m3/mol):343.8
3. Isotonic specific volume (90.2K): 885.9
4. Surface tension (dyne/cm): 44.0
5. Polarizability（10-24 cm3):45.31
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 3
3. Number of hydrogen bond acceptors: 8
4. Number of rotatable chemical bonds: 6
5. Number of tautomers: none
6. Topological molecule polar surface area 55.2
7. Number of heavy atoms: 32
8. Surface charge: 0
9. Complexity: 544
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 3
Properties and stability
Stable under normal temperature and pressure.
2. Molar volume (m3/mol):343.8
3. Isotonic specific volume (90.2K): 885.9
4. Surface tension (dyne/cm): 44.0
5. Polarizability（10-24 cm3):45.31
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 3
3. Number of hydrogen bond acceptors: 8
4. Number of rotatable chemical bonds: 6
5. Number of tautomers: none
6. Topological molecule polar surface area 55.2
7. Number of heavy atoms: 32
8. Surface charge: 0
9. Complexity: 544
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 3
Properties and stability
Stable under normal temperature and pressure.
Incompatible materials:Strong oxidizing agentStorage method
Seal and store in a dry and cool place.
Synthesis method
None
Purpose
Strong tranquillizer. It is said to be used for acute and chronic schizophrenia, and has a significant effect on delusional and nervous types.
i-font-family: ‘Times New Roman’; mso-hansi-font-family: ‘Times New Roman’; mso-bidi-font-family: ‘Times New Roman’; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA”>Incompatible materials:
Strong oxidizing agentStorage method
Seal and store in a dry and cool place.
Synthesis method
None
Purpose
Strong tranquillizer. It is said to be used for acute and chronic schizophrenia, and has a significant effect on delusional and nervous types.
