3-dihydrobenzene Preparation method of imidazole-2-one maleate_Kain Industrial Additive

Background and overview[1][2] 5-Chloro-1-[1-[3-(2-oxo-1,3-dihydrobenzimidazol-1-yl)propyl]-4-piperidinyl]-1,3- Dihydrobenzimidazole-2-one maleate is domperidone maleate. Domperidone maleate is a peripheral dopamine receptor blocker that directly acts on the gastrointestinal wall. It can increase the tension of the lower esophageal sphincter, prevent gastro-esophageal reflux, enhance gastric motility, promote gastric emptying, and coordinate the stomach and duodenum. Exercise can inhibit nausea and vomiting,…