4-benzoxazin-3(4H)-one_Kain Industrial Additive

Background and overview[1][2] 6-Bromo-2H-1,4-benzoxazin-3(4H)-one is an organic intermediate that can be prepared in one step. A class of drugs with PPAR agonistic activity can be prepared. Preparation[1-2] Method 1 Weigh 2-amino-4-bromophenol (2.5g, 13mmol) and add it to the three-necked flask, measure 80mL of tetrahydrofuran and add it to the system, and measure and add triethylamine…