Application of 2,4-dichloro-5-methoxyaniline_Kain Industrial Additive

Background and overview[1] 2,4-Dichloro-5-methoxyaniline CAS number 98446-49-2, chemical formula C7H7Cl2NO. Molecular weight 247.06100. White or off-white powder, density 1.375 g/cm3, melting point 51 °C, boiling point 290.1ºC at 760 mmHg, flash point 129.3ºC, refractive index 1.587. 2,4-Dichloro-5-methoxyaniline is mainly used in the preparation of primary Sutinib intermediate 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-(3-chloropropoxy)-3-quinolinecarbonitrile . Bosutinib, developed by Wyeth Pharmaceuticals in…

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