4-dihydro-3-hydroxy-4-oxy-1

Background and overview[1] 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine is a heterocyclic organic compound and a polypeptide synthesis condensation agent, referred to as HOOBt. Compared with urea salts such as HBTU and HATU (phosphorus-(7-azabenyltriazol-1-yl)-1,1,3,3-tetramethylurea hexafluorophosphate), HOOBt is not only low in cost, but also more important What is unique is that in the condensation reaction, there is no side reaction…