Preparation of (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester_Kain Industrial Additive

Background and overview[1] (4S,5R)-2-(4-Methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester is a pharmaceutical intermediate, which can be made from ( 2′R,3′S)-phenylisoserine methyl ester and p-toluic acid were prepared in three steps. There are reports in the literature that (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester can be used to prepare an anti-tumor activity A novel taxane antitumor compound derived from the…

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