5-tetrahydro-2H-1-benzazepine-2-one_Kain Industrial Additive

Background and Overview[1] 3-Bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one is an intermediate in the synthesis of benazepril hydrochloride. Benazepril hydrochloride is a first-line antihypertensive drug recommended by the World Health Organization. It is a chiral drug with good clinical efficacy, high safety and few side effects among the current international angiotensin-converting enzyme inhibitor antihypertensive drugs. . 3-bromo-1,3,4,5-tetrahydro-2H-1-benzazepine-2-one Preparation[2] The synthesis…