6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate_Kain Industrial Additives

Background and overview[1] 2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate is a A kind of azaspirocyclic compound, often used as an intermediate in drug synthesis. There are reports in the literature that it can bind to Autotaxin and act as an Autotaxin inhibitor. Preparation[1] (1) 1-benzoylazetidine-3-carboxylic acid methyl ester (compound 1 -1) Preparation. Take a 250mL single-neck…