6-dichloro-3-(trifluoromethyl)benzoic acid_Kain Industrial Additive

Background and overview[1] 2,6-Dichloro-3-(trifluoromethyl)benzoic acid is an organic intermediate that can be prepared from 2,4-dichloro-1-(trifluoromethyl)benzoic acid through a two-step reaction. . Starting from 2,4-dichlorotrifluorotoluene, the reaction was continuously treated with butyllithium and dry ice to obtain 2,6-dichloro-3-(trifluoromethyl)benzoic acid with a yield of 75%. Preparation method[1] A solution of 2,4-dichloro-1-(trifluoromethyl)benzene (3.6 mL, 5.4 g, 25 mmol)…