Application of 1-(3-ethoxy-4-methoxyphenyl)-2-(methanesulfonyl)ethanone_Kain Industrial Additive

Background and overview[1] 1-(3-ethoxy-4-methoxyphenyl)-2-(methanesulfonyl)ethanone can be used to prepare the Apremilast intermediate 1-(3-ethoxy-4- Methoxy)phenyl-2-methanesulfonylethylamine. As an oral small molecule PDE-4 inhibitor, Apremilast is cheaper and more convenient than biologics for injection; it has good safety profile: it has fewer side effects than other PDE-4 inhibitors, and it expands the applicable population. Therefore, Apremilast has a…