Application of 2-bromo-3-methylphenol_Kain Industrial Additive

Background and Overview 2-Bromo-3-methylphenol is a phenol derivative that can be used as an organic raw material for the preparation of pharmaceutical intermediates. Preparation[1] Dissolve 2-amino-m-cresol 8a (5.7g, 46.3mmol) in H2O (30mL) and 1,4-dioxane (15mL). The mixture was heated to reflux, then HBr (48%, 17 mL, 0.31 mol) was added dropwise over 20 min. After…