Application of 2-bromo-4-methoxyaniline_Kain Industrial Additives

Background and overview[1][2] 2-Bromo-4-methoxyaniline is an important pharmaceutical intermediate and can be used as an important intermediate for anti-cancer drug AZD9291 and cerebral circulation, anti-asthma and anti-ulcer drugs. 6-hydroxy-2(1H) – Quinolinones and their derivatives. Preparation[1] Yuan Jiacheng et al. reported the use of 1-butyl-3-methylimidazole tribromide ([ bmim] Br3) as the brominating agent to synthesize 2-bromo-4-methoxy…