Application of 3,3′-diaminobenzidine_Kain Industrial Additive
Background and overview[1][2] The selenium reagent is abbreviated as DAB, and its scientific name is 3,3′-diaminobenzidine. It reacts with Se (W) in an acidic medium to form a yellow stem. DAB is an alkali that darkens quickly in the air. Its hydrochloric acid Salt is a white needle-shaped substance, soluble in water, and its aqueous…
Application of 3,5-diiodo-4-hydroxybenzaldehyde_Kain Industrial Additive
Background and overview[1] 3,5-Diiodo-4-hydroxybenzaldehyde can be used as a pharmaceutical synthesis intermediate. If 3,5-diiodo-4-hydroxybenzaldehyde is inhaled, move the patient to fresh air; if skin contact occurs, take off contaminated clothing, rinse the skin thoroughly with soap and water, and seek medical attention if you feel unwell. ; If eye contact occurs, separate eyelids, rinse with…
Application of 3,4-dimethoxyphenylacetic acid_Kain Industrial Additive
Background and overview[1][2] 3,4-Dimethoxyphenylacetic acid, also known as homoveratrol acid, can be used to synthesize the beta-blocker drug bevantolol and the antiarrhythmic drug verapamil, etc. It is also a key intermediate in the synthesis of isoquinoline alkaloids. Preparation method[1] Preparation of ethyl 3,4-dimethoxyacetophenonate (3): Add anhydrous aluminum trichloride (14.7 g, 0.11 mol), methylene chloride (110…
Application of 3,4-dichlorobenzeneglyoxal hydrate_Kain Industrial Additive
Overview[1] 3,4-Dichlorophenylglyoxal hydrate is the monohydrate of 3,4-dichlorophenylglyoxal. 3,4-Dichlorophenylglyoxal is an organic intermediate and has been reported to be used in the preparation of c-Met inhibitors. Apply[1] CN201010579221.0 reports [1,2,4]triazolo[4,3‑b][1,2,4]triazine compounds, pharmaceutically acceptable salts thereof, prodrugs thereof and hydrates thereof or Solvates, also relate to methods for the preparation of said compounds, pharmaceutical compositions containing…
Application of 3,5-dicarboxybenzeneboronic acid_Kain Industrial Additive
Background and overview[1] 3,5-dicarboxyphenylboronic acid can be used as a pharmaceutical synthesis intermediate. It is an important intermediate for the synthesis of drugs, pesticides, liquid crystals, etc. Its application fields are constantly expanding and it has attracted people’s attention. In addition, aromatic carboxylic acids play an important role as ligands in coordination polymers and assembled…
Application of 3,5-di-tert-butyl-p-hydroxybenzaldehyde_Kain Industrial Additive
Background and overview[1] 3,5-Di-tert-butyl-p-hydroxybenzaldehyde is an aldehyde organic compound that can be used as an intermediate in organic synthesis. Preparation[1-2] Method 1: Synthesis of 3,5-di-tert-butyl-4-hydroxybenzaldehyde: Add 2.42mL POCl3 (0.026mol) to 2.01mLDMF (0.026mol) at 0°C, stir until a white solid is produced, add Dissolve in 20 mL of 1,2-dichloroethane to obtain solution A. Dissolve 4.12g of…
Application of 3,5-dimethylanisole_Kain Industrial Additive
Background and overview[1][2] 3,5-Dimethylanisole is an ether organic compound that can be used as an organic intermediate. It can be prepared from 3,5-dimethylphenol to ether in one step. Preparation[1] Preparation of 3,5-dimethylanisole: 3,5-xylenol (10g, 0.082mol) and anhydrous potassium carbonate (34g, 0.25mol) were added to DMF (150ml), and methyl iodide (12.8g, 0.090mol) was added dropwise in…
Application of 3,4-dihydro-3-hydroxy-4-oxy-1,2,3-benzotriazine_Kain Industrial Additive
Background and overview[1] 3,4-Dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine is a heterocyclic organic compound and a polypeptide synthesis condensation agent, referred to as HOOBt. Compared with urea salts such as HBTU and HATU (phosphorus-(7-azabenyltriazol-1-yl)-1,1,3,3-tetramethylurea hexafluorophosphate), HOOBt is not only low in cost, but also more important What is unique is that in the condensation reaction, there is no side reaction…
