Application of 4-aldehyde benzocyclobutene_Kain Industrial Additive

Background and overview[1] 4-Aldehyde benzocyclobutene is an organic intermediate that can be prepared from 4-bromobenzocyclobutene. Preparation[1] Add 50 mL of anhydrous tetrahydrofuran (THF), Mg chips (2.88 g, 120 mmol) and 1,2-dibromoethane (4 drops) into a 500 mL flask. The reaction mixture was then heated at reflux for 15 minutes. A solution of 4-bromobenzocyclobutene (1.1, 20…