Mitsunobu reaction_Kain Industrial Additive

Mitsunobu reaction (Mitsunobu reaction) is a bimolecular nucleophilic substitution reaction (SN2 reaction). In 1967, Mitsunobu reported a new method for the condensation of acids and alcohols into esters under the action of triphenylphosphine (PPh3) and diethyl azodicarboxylate (DEAD). When the substrate is a secondary alcohol, the configuration of the carbon atom connected to the hydroxyl…