Preparation and application of 2-nitro-5-chloroaniline_Kain Industrial Additive

Background and overview[1] 2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It is currently used in fenbendazole, an upgraded product of the veterinary drug albendazole, and has broad market prospects. Preparation[1] Synthesis of 1, 2,4-dichloronitrobenzene Add 0.714mol concentrated sulfuric acid into a 250mL flask, then slowly add 0.701mol 95% nitric acid dropwise, cool and…