Preparation and application of (4-chlorophenyl)glyoxylic acid_Kain Industrial Additive

Background and overview[1] (4-Chlorophenyl)glyoxylic acid is a pharmaceutical intermediate that can be prepared from chlorobenzene and ethyl 2-chloro-2-oxoacetate in two steps. It can be used to prepare a drug that can be used to treat and Compounds for KIT and PDGFR-related disorders Preparation[1] Step 1: Synthesis of ethyl 2-(4-chlorophenyl)-2-oxoacetate To a stirred solution of chlorobenzene…