Preparation and application of benzophenone oxime_Kain Industrial Additive

Background and overview[1] Parecoxib is a specific inhibitor of cyclooxygenase-2 (COX-2), a prodrug of valdecoxib, and a coxib analgesic among anti-arthritic drugs. . Parecoxib is used for the short-term treatment of postoperative pain. The sodium salt of parecoxib is used clinically as an injection. Benzophenone oxime is an intermediate in the preparation of parecoxib. Preparation[1]…