preparation and application of o-chloroacetophenone_kain industrial additive

background and overview[1-3] o-chloroacetophenone is a pharmaceutical chemical raw material used in the preparation of chlorbendarol and other drugs. can be prepared from o-chlorostyrene. ​ preparation[1] in a 50ml reactor, add 1mmol o-chlorostyrene, 0.1mmol palladium/carbon and 5ml ethanol, stir and raise the temperature to 35°c, add 0.02mmol and mass fraction of nitric acid in sequence…

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