Preparation and application of o-chloroacetophenone_Kain Industrial Additive
Background and overview[1-3] O-chloroacetophenone is a pharmaceutical chemical raw material used in the preparation of chlorbendarol and other drugs. Can be prepared from o-chlorostyrene. Preparation[1] In a 50mL reactor, add 1mmol o-chlorostyrene, 0.1mmol palladium/carbon and 5mL ethanol, stir and raise the temperature to 35°C, add 0.02mmol and mass fraction of nitric acid in sequence…
