Preparation method of 2-bromo-3-fluorophenol_Kain Industrial Additive

Background and overview[1] 2-Bromo-3-fluorophenol is a chemical intermediate. Preparation[1] Step 1: Put sodium hydrogen (0.96 g, 40 mmol) into tetrahydrofuran (20 mL), and slowly add trifluorophenol (20 mmol) in tetrahydrofuran solution (5 mL) dropwise to the above system at room temperature. After stirring for two hours, A solution of N, N-dimethylcarbamoyl chloride (5.42 g, 40…