Preparation method of 3-hydroxyanthranizoic acid hydrochloride_Kain Industrial Additive

Background and overview[1] 3-Hydroxyanthranilic hydrochloride can be used as a pharmaceutical synthesis intermediate. Preparation[1] The preparation of 3-hydroxyanthranilic acid hydrochloride is as follows: Penicillium is used to catalyze the preparation of 3-hydroxyanthranilic acid, and the reaction formula is as follows: The substrate 2-aminophenol (1) is reacted catalyzed by Penicillium to obtain the product 3-hydroxyanthranilic acid…