Preparation method of 4-(aminomethyl)benzene-1-sulfonic acid_Kain Industrial Additive

Background and overview[1] 4-(Aminomethyl)benzene-1-sulfonic acid can be used as a pharmaceutical synthesis intermediate. Preparation[1-2] 4-(Aminomethyl)benzene-1-sulfonic acid is prepared as follows: Method 1: Add 10ml benzylamine dropwise to 30ml 20% fuming H2SO4 at 0°C with stirring. The mixture was warmed to room temperature and stirred for 30 minutes, then to 80°C for 1 hour. After cooling…