Preparation method of 4-bromomethylphenylacetic acid_Kain Industrial Additive

Overview[1][2] 4-Bromomethylphenylacetic acid is a common organic synthesis intermediate and is widely used in the synthesis of pesticides and pharmaceutical intermediates. Preparation method[1-2] Method 1 Dissolve 50g of compound 1 (4-methylphenylacetic acid) into 200 ml of carbon tetrachloride, heat to reflux, and add NBS (N-bromosuccinimide) (62g) in batches while heating. 0.35mol), continue to maintain the…