Preparation method of Boc-D-homophenylalanine_Kain Industrial Additive

Overview Boc-D-Homophenylalanine is an amino acid raw material that can be used to prepare peptides. Preparation method[1-2] Method 1. Chacko et al. reported that Boc-D-homophenylalanine can be synthesized through the following route. Method 2, Preparation of (2R)-N-amino-2-[(tert-butoxy)carbonylamino]-4-phenylbutanamide: HD-Hphe-OH (44.0g, 245mmol) in 1:1 H2O/t-BuOH (350 mL) was treated with powdered NaOH (10.8 g, 270 mmol) at…