Preparation method of cyclohexylmandelic acid_Kain Industrial Additive

[Background and Overview][1][2] Among a large number of asymmetric synthesis pharmaceutical reagents, the chiral compound α-cyclohexylmandelic acid (Cyclohexylphenylglycolic Acid, referred to as CHPGA) is an important precursor synthesis raw material. Its two optical isomers are (S)-α-cyclohexylmandelic acid and (R)-α-cyclohexylmandelic acid. (S)-α-Cyclohexylmandelic acid is the precursor material for the synthesis of antispasmodic drugs (S)-oxybutynin and (S)-desethylated…