Preparation method of dehydronitroso-nifedipine_Kain Industrial Additive

Background and overview[1][2] Dehydronitrosonifedipine is an impurity of nifedipine. Nifedipine is a dihydropyridine calcium antagonist that can selectively inhibit the transmembrane transport of calcium ions into cardiomyocytes and smooth muscle cells, and inhibit the release of calcium ions from intracellular stores without changing plasma calcium ion concentration. It is currently recognized as One of the…