Preparation method of dibenzo[b

Background and overview[1] Dibenzo[b,f][1,4]thiazepin-11-[10H]one is a key intermediate in the preparation of quetiapine. Quetiapine, generally sold as the hemifumarate salt. It is an antipsychotic drug developed by AstraZeneca UKlimited (AstraZeneca Pharmaceutical Company). It was first launched in the UK in November 1997 and is used to treat schizophrenia. It has strong antipsychotic effects and causes…