Preparation of (1R,2R)-1,2-diphenylethylenediamine_Kain Industrial Additive
Background and overview[1][2] Optically active (1S, 2S)-(-)-1,2-diphenylethylenediamine; (1R,2R)-1,2-diphenylethylenediamine is an important chirality Reagents have been widely used in asymmetric synthesis and optical resolution, such as asymmetric hydroxylation reactions of alkenes, asymmetric aldol condensation reactions, asymmetric Diels-Alder reactions, asymmetric allylation reactions of carbonyl groups, optical activity The synthesis of allenyl alcohol and propynyl alcohol, the asymmetric…
Preparation of (1R,2R)-(+)-1,2-diaminocyclohexane-N,N’-bis(2-phenylphosphine-1-naphthoyl)_Kain Industrial Additive
Background and overview[1] (1R,2R)-(+)-1,2-diaminocyclohexane-N,N’-bis(2-phenylphosphine-1-naphthoyl) is an organic phosphine ligand commonly used in transition metal catalyzed reactions. This chiral coordination has proven to be very successful in the amination of butadiene monoepoxides, a type of epoxide and a potential prospect for asymmetric synthesis starting materials (or substrates). Preparation[1] Add 1.90g (5.33mmol) 2-diphenylphosphine-1-naphthoic acid and 42ml dichloromethane…
