Preparation of 2-benzyl-5-chloro-1

Background[1][2] 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine can be used as a pharmaceutical synthesis intermediate and an organic synthesis intermediate, mainly used in experiments Laboratory research and development process and chemical and pharmaceutical synthesis process. Preparation[1] 2-Benzyl-5-chloro-1,2,3,4-tetrahydro-[2,6]naphthyridine is prepared as follows: Step 1: N-ethoxy-3-methylpyridinium iodide: Add 3-methylpyridine-N-oxide (50.00g, 458mmol) and anhydrous dichloromethane (90mL) to the round-bottomed flask. Ethyl iodide (715.57g,…