Preparation of 2-bromo-5-trifluoromethoxyaniline_Kain Industrial Additive

Background and overview[1] 2-Bromo-5-trifluoromethoxyaniline is a chemical intermediate Preparation[1] A solution of 3-trifluoromethoxy-aniline (1.77g) in toluene (20ml) was treated with N-bromosuccinimide (1.87g) at ambient temperature and the reaction mixture was Stir for 2 hours, quench by adding water and extract the mixture with ethyl acetate (3x50ml). The combined organic extracts were washed with aqueous sodium…