Preparation of 3,4-dichlorophenylmethylsulfonyl chloride_Kain Industrial Additive
Background and overview[1] 3,4-Dichlorophenylmethylsulfonyl chloride can be used as a pharmaceutical and chemical synthesis intermediate. If 3,4-dichlorophenylmethylsulfonyl chloride is inhaled, please move the patient to fresh air; if there is skin contact, take off contaminated clothing, wash the skin thoroughly with soap and water, and seek medical treatment if you feel uncomfortable; If eye contact…
Preparation of 3,4-dibromobenzoic acid_Kain Industrial Additive
Background and overview[1][2] 3,4-Dibromobenzoic acid is colorless crystal at room temperature, with a boiling point of 276°C. It is widely used as a pharmaceutical intermediate. In polymer plastic molding and processing, it is used as a special plasticizer, a compound or mixture of compounds added to polymer resins to provide flexibility and toughness. In recent…
Preparation of 3,5-diethyl-1,2-dihydro-1-phenyl-2-propylpyridine_Kain Industrial Additive
Background and overview[1] 3,5-diethyl-1,2-dihydro-1-phenyl-2-propylpyridine can be used as a pharmaceutical synthesis intermediate. If 3,5-diethyl-1,2-dihydro-1-phenyl-2-propylpyridine is inhaled, move the patient to fresh air; if skin contact occurs, remove contaminated clothing and wash with soap Rinse the skin thoroughly with water and clean water. If you feel discomfort, seek medical treatment; if the eye contact occurs, separate…
Preparation of 3,5-bis(trifluoromethyl)phenyl isothiocyanate_Kain Industrial Additive
Background and overview[1] 3,5-Bis(trifluoromethyl)phenyl isothiocyanate is mainly used as an intermediate in pharmaceutical synthesis, such as the preparation of a series of thiourea compounds containing aromatic amine structures. This series of compounds has good properties with drug targets. The matching pattern has good inhibitory activity against tumor cell lines in vitro and can be used…
Preparation of (3,5-dimethoxyphenyl)acetic acid_Kain Industrial Additive
Overview[1] Bis- or polymethoxy-substituted phenylacetic acid is an important organic synthesis intermediate and is widely used in medicine and dyes. For example: (3,5-dimethoxyphenyl)acetic acid is used as raw material to synthesize pterostilbene with anti-cancer activity; 3,4,5-trimethoxyphenylacetic acid is used as raw material to synthesize highly active anti-tumor drug CA4; 2,4-Dimethoxyphenylacetic acid is a key intermediate…
Preparation of 3,4,5-trimethoxybromobenzene_Kain Industrial Additive
Background and overview[1] 3,4,5-Trimethoxybromobenzene can be used as a pharmaceutical synthesis intermediate. It can be prepared by the reaction of 5-bromo-1,2,3 trihydroxybenzene and dimethyl sulfate, or it can also be prepared from 4-bromo-2 , 6-dimethoxyphenol was prepared as the reaction raw material. Preparation[1-2] Option 1, Cool the mixture of 5-bromo-1,2,3 trihydroxybenzene (1.3g, 5.63mmol), 1M NaOH…
Preparation of 3,4-difluorobenzoic acid_Kain Industrial Additive
Background and overview[1] Substituted benzoic acid 3,4-difluorobenzoic acid is an organic synthesis intermediate that can be focused on development. It can be used in the production of organic chemical raw materials and various pesticides. It is also a synthetic intermediate for dyes, pesticides and medicines. 3,4-Difluorobenzoic acid is a raw material for preservatives and fragrances.…
Preparation of 3,3-dichloro-1-(4-nitrophenyl)-2-piperidone_Kain Industrial Additive
Background and overview[1] 3,3-Dichloro-1-(4-nitrophenyl)-2-piperidone is an important pharmaceutical intermediate, for example, it can be used to prepare apixaban derivatives. Apixaban is a small molecule selective FXa inhibitor of pyrazole derivatives. Similar to rivaroxaban, apixaban has two binding sites for factor Xa. The 4-methoxyphenyl moiety in the apixaban structure binds to the S1 pocket of factor…
Preparation of 3,3’5,5′-tetramethylbiphenyl bisphenol diglycidyl ether_Kain Industrial Additive
Background and overview[1][2] Electronic materials are the basis for the development of the microelectronics industry. As the main structural material for the production of integrated circuits, epoxy plastic sealants are also developing rapidly with the development of chip technology, and the development of plastic sealant technology will greatly promote the microelectronics industry. development of. Biphenyl…
Preparation of 3,5-dichlorobenzoyl chloride_Kain Industrial Additive
Background and overview[1] 3,5-Dichlorobenzoyl chloride is an important pesticide, pharmaceutical, and dye intermediate. In pesticide production, pesticides can be prepared through benzoic acidification reactions; in the pharmaceutical field, drugs for treating headaches and drugs for balancing antidiuretic hormone can be produced. In recent years, it has also been used to prepare purine derivatives, which are…
