Preparation of 3-amino-4-chlorobenzonitrile_Kain Industrial Additive

Background and overview[1-2] 3-Amino-4-chlorobenzonitrile is a pharmaceutical intermediate. It can be nitrated from p-chlorobenzonitrile to obtain 4-chloro-3-nitrobenzonitrile, and then reduced to obtain 3-amino-4-chlorobenzonitrile. Carbonitrile. There are reports in the literature that 3-amino-4-chlorobenzonitrile can be used to prepare 2-amino-4-cyano-3′,4′-difluoro-1,1′-biphenyl, and fluorinated benzidine is an important class of The intermediates are widely used in industrial production fields…