Preparation of 3-bromo-2-methylbenzaldehyde_Kain Industrial Additive

Background and overview[1][2] 3-Bromo-2-methylbenzaldehyde can be used as a pharmaceutical synthesis intermediate, which can be reduced from 3-bromo-2-methylbenzoic acid as the starting material to obtain (3-bromo-2-methylphenyl ) methanol, and then oxidized to prepare 3-bromo-2-methylbenzaldehyde. Preparation[1-2] Report 1: Step 1: To a suspension of sodium borohydride (0.630 g, 16.7 mmol) in THF (82 mL), add 3-bromo-2-methylbenzoic…