Preparation of 4-[4-[(5S)-5-(aminomethyl)-2-carbonyl-3-zolidinyl]phenyl]-3-morpholinone_Kain Industrial Additive

Background and overview[1][2] 4-[4-[(5S)-5-(aminomethyl)-2-carbonyl-3-zolidinyl]phenyl]-3-morpholinone is an intermediate for the preparation of rivaroxaban, Rivaroxaban is a new type of anticoagulant that can be taken directly orally. It directly inhibits activated coagulation factor In 2008, rivaroxaban was approved for marketing in Canada and the European Union under the trade name Xarelto. On July 1, 2011, Johnson &…