Preparation of 4-bibenzoic acid_Kain Industrial Additives

Background and overview[1] 4-Biphenylcarboxylic acid can be used as an intermediate in pharmaceutical synthesis, such as preparing biphenyldiazole derivatives. In vitro antibacterial activity tests show that this type of compound has strong antifungal and antibacterial activity. Preparation[1] Method 1: Preparation of 4-bibenzoic acid. Under argon protection, add 2.75g (13.8mmol) of 4-bromobenzoic acid, 2g (16.4mmol) of…