Preparation of 4-carboxyphenylhydrazine hydrochloride_Kain Industrial Additive

Background and overview[1][2] 4-Carboxyphenylhydrazine hydrochloride is an important intermediate, especially a pharmaceutical intermediate. The existing technology uses p-aminobenzoic acid as raw material, and is prepared through diazotization reaction, sodium sulfite reduction, and hydrolysis. The synthesis method of the obtained 4-carboxyphenylhydrazine hydrochloride requires a long reaction time, generally requires a yield of only 63-72%, and has…