Preparation of 4-(chloromethyl)benzaldehyde_Kain Industrial Additive

Background and overview[1-3] 4-(Chloromethyl)benzaldehyde is an organic intermediate commonly used as raw material for pharmaceutical synthesis. It can be obtained by one-step oxidation of 4-chloromethylbenzyl alcohol. Preparation[1-3] Method 1 Report 1 Dissolve pyridinium chlorochromate (4.96 g, 23.0 mmol, 1.2 equiv) in 60 mL CH2Cl2, then add 4-chloromethyl Benzyl alcohol (3.00g, 19.2 mmol) was stirred. The…