Preparation of 5,6-diphenyl-2-hydroxypyrazine_Kain Industrial Additive
Background and overview[1] 5,6-Diphenyl-2-hydroxypyrazine is a pharmaceutical intermediate that can be prepared in one step from benzoyl and aminoacetamide hydrochloride. There are reports in the literature that 5,6-diphenyl-2-hydroxypyrazine can be used to prepare IP receptor agonists (Compound I). The diseases that IP receptor agonists can treat mainly include pulmonary arterial hypertension (PAH), PAH related to…
Preparation of 5,12-bis(phenylethynyl)tetracene_Kain Industrial Additive
Background and overview[1] 5,12-Bis(phenylethynyl)tetracene is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory research and development processes and chemical and pharmaceutical research and development processes. Preparation[1] 5,12-bis(phenylethynyl)tetracene is prepared as follows: 1) Add 51.0g (0.50 mol) of anhydrous dioxane to a suspension of 11.5 g (0.50 mol) of lithium amide…
