Preparation of niraparib p-toluenesulfonate_Kain Industrial Additive

Background and overview[1][2] Niraparib p-toluenesulfonate is a sulfonic acid organic compound that can be used as a pharmaceutical intermediate. The chemical name of niraparib is 2-[4-((3S)-3-piperidinyl)phenyl]-2H-indazole-7-formyl. It is an oral polyADP ribose polymer developed by Tesaro Company. Enzyme (PARP) inhibitors can inhibit cells from repairing DNA damage, mainly targeting cancers with BRCA mutations, such as…