Synthesis of 5,6-dihydro-3-(4-morpholino-1-piperidinyl)phenyl]-2(1H)-pyridone_Kain Industrial Additive
Background and overview[1] 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidyl)phenyl]-2(1H)-pyridone is a One of the impurities in Pixaban. Apixaban is an oral, selective activated factor X inhibitor jointly developed by Pfizer and Bristol-Myers Squibb. In January 2013, it obtained the import drug license issued by the State Food and Drug Administration of China and was officially launched in China in April…
