There are many synthesis methods for citrulline (Cit) and broad application prospects.

Citrulline (Cit), also known as carbamoylornithine, refers to an α-amino acid generated from ornithine and carbamoyl phosphate in the urea cycle, with the chemical formula C6H13N3O3. Citrulline appears as a white crystalline powder with a mild and slightly sweet smell. It is slightly soluble in alcohol, easily soluble in water, and insoluble in ether. Citrulline…